The sequence of the Cu–Zn superoxide dismutase gene ofDrosophila
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منابع مشابه
CuZn - superoxide dismutase ( CuZnSOD ) transgenic mice show
_, We have used female and male transgenic (Tg) mice that carry the complete sequence of the human copper-zinc (CuZn) , superoxide dismutase (SOD) gene in order to assess the lethal effects of methylenedioxyamphetamine (MDA) and methylene,_ im dioxymethamphetamine (MDMA). In contrast to non-Tg mice, both heterozygous and homozygous SOD-Tg mice showed resistance to the lethal effects of both dru...
متن کاملMolecular immunocytochemistry of the CuZn superoxide dismutase in rat hepatocytes
The distribution of CuZn superoxide dismutase (SOD) molecules in subcellular organelles in rat liver hepatocytes was studied using integrated biochemical, stereological, and quantitative immunocytochemical techniques. A known concentration of purified CuZn SOD in 10% gelatin was embedded alongside the liver tissue for the calculation of CuZn SOD concentrations in hepatocyte organelles and total...
متن کاملHypertrophy of cerebral arterioles in mice deficient in expression of the gene for CuZn superoxide dismutase.
BACKGROUND AND PURPOSE Reactive oxygen species are believed to be an important determinant of vascular growth. We examined effects of genetic deficiency of copper-zinc superoxide dismutase (CuZnSOD; SOD1) on structure and function of cerebral arterioles. METHODS Systemic arterial pressure (SAP) and cross-sectional area of the vessel wall (CSA) and superoxide (O2-) levels (relative fluorescenc...
متن کاملSuperoxide Dismutase Hypertrophy of Cerebral Arterioles in Mice Deficient in Expression of the Gene for CuZn
Superoxide Dismutase Hypertrophy of Cerebral Arterioles in Mice Deficient in Expression of the Gene for CuZn Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2006 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/01.STR.0000227236.84546.5a 2006;37:1850-1855; originally publi...
متن کاملOPTIMIZATION OF THE TRICHODERMA HARZIANUM CuZn SUPEROXIDE DISMUTASE GENE EXPRESSION IN E. COLI
A study of the optimization of CuZn superoxide dismutase gene expression in E. coli L21/pET28-SOD was undertaken. The SOD gene was directionally cloned into expression vector pET28.The recombinant plasmid was transformed into E. coli BL21 and induced by IPTG to express SOD protein. The four effective factors, including the initial concentration of BL21/pET28-SOD, concentration of IPTG, incubati...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1987
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/15.24.10601